{"id":1175,"date":"2026-10-04T18:46:48","date_gmt":"2026-10-04T18:46:48","guid":{"rendered":"https:\/\/muhammetozgehan.com\/atteinte-capillaire-des-infections-systemiques-syphilis-secondaire-et-alopecie-mitee\/"},"modified":"2026-10-10T14:21:36","modified_gmt":"2026-10-10T14:21:36","slug":"atteinte-capillaire-des-infections-systemiques-syphilis-secondaire-et-alopecie-mitee","status":"publish","type":"page","link":"https:\/\/muhammetozgehan.com\/fr\/atteinte-capillaire-des-infections-systemiques-syphilis-secondaire-et-alopecie-mitee\/","title":{"rendered":"Atteinte capillaire des infections syst\u00e9miques (Syphilis secondaire et alop\u00e9cie \u00ab mit\u00e9e \u00bb)"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1175\" class=\"elementor elementor-1175 elementor-329\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-641f0bb e-flex e-con-boxed e-con e-parent\" data-id=\"641f0bb\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-550288b elementor-widget elementor-widget-html\" data-id=\"550288b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div class=\"medical-guide-page-wrapper\">\r\n    <!-- Sayfa \u00dcst\u00fc K\u00fcresel Ba\u015fl\u0131k & Logo Alan\u0131 -->\r\n    <div class=\"guide-hero\">\r\n        <div class=\"hero-title-wrapper\">\r\n            <div class=\"hero-logo-box\">\r\n                <img decoding=\"async\" src=\"https:\/\/muhammetozgehan.com\/wp-content\/uploads\/2026\/10\/logo-seffaf.png\" alt=\"Logo du Dr Muhammet \u00d6zgehan\" width=\"32\" height=\"32\" class=\"hero-inline-logo\" title=\"\">\r\n            <\/div>\r\n            <h2>Encyclop\u00e9die M\u00e9dicale Capillaire<\/h2>\r\n        <\/div>\r\n        <p class=\"guide-subtitle\">Pathologies dermatologiques et guides cliniques fond\u00e9s sur des preuves, selon les normes internationales.<\/p>\r\n    <\/div>\r\n\r\n    <!-- Ana Makale Konteyneri -->\r\n    <article class=\"medical-article-card\">\r\n        <div class=\"article-header\">\r\n            <span class=\"article-category\">GUIDE CLINIQUE & PATHOLOGIE<\/span>\r\n            <h1>Atteinte capillaire des infections syst\u00e9miques (Syphilis secondaire et alop\u00e9cie \u00ab mit\u00e9e \u00bb) \u2013 Guide de diagnostic et de traitement<\/h1>\r\n            <div class=\"author-meta-box\">\r\n                <p><strong>Pr\u00e9par\u00e9 par :<\/strong> Dr. Muhammet \u00d6zgehan | Association Turque des Maladies des Cheveux et du Cuir Chevelu<\/p>\r\n                <p class=\"compilation-note\"><em>Ce guide a \u00e9t\u00e9 compil\u00e9 par le Dr Muhammet \u00d6zgehan, en se basant sur la litt\u00e9rature actuelle.<\/em><\/p>\r\n            <\/div>\r\n        <\/div>\r\n\r\n        <!-- Medikal \u0130ll\u00fcstrasyon Alan\u0131 -->\r\n        <div class=\"medical-illustration-box\">\r\n            <img decoding=\"async\" src=\"https:\/\/sachastaliklari.org.tr\/wp-content\/uploads\/2026\/09\/sistemik-enfeksiyonlar-sekonder-sifiliz-guve-yemis-alopesi-dr-muhammet-ozgehan.png\" alt=\"Illustration clinique de l&#039;alop\u00e9cie due \u00e0 une infection syst\u00e9mique de la syphilis secondaire\" title=\"\">\r\n        <\/div>\r\n\r\n        <!-- Hasta Bilgilendirme B\u00f6l\u00fcm\u00fc -->\r\n        <section class=\"patient-info-box\">\r\n            <h3>\ud83d\udccc Section d'Information pour les Patients : Que Signifie Cette Condition ?<\/h3>\r\n            <p>Au cours de la deuxi\u00e8me phase de la syphilis, une infection syst\u00e9mique sexuellement transmissible, un tableau tr\u00e8s caract\u00e9ristique de perte de cheveux peut appara\u00eetre sur le cuir chevelu, en plus des sympt\u00f4mes g\u00e9n\u00e9raux observ\u00e9s dans le corps.<\/p>\r\n            <ul class=\"styled-list\">\r\n                <li><strong>Qu'est-ce que l'alop\u00e9cie \u00ab mit\u00e9e \u00bb ?:<\/strong> Sur le cuir chevelu, en particulier dans les r\u00e9gions occipitales (nuque) et temporales (tempes), de multiples petites zones de perte de cheveux, diffuses et de la taille d'une pi\u00e8ce de monnaie, apparaissent sans limites nettes. L'apparence est similaire \u00e0 un tissu rong\u00e9 par les mites. <\/li>\r\n                <li><strong>Autres signes:<\/strong> Des \u00e9ruptions cutan\u00e9es rouge p\u00e2le sur les paumes et les plantes des pieds, un gonflement g\u00e9n\u00e9ralis\u00e9 des ganglions lymphatiques et des l\u00e9sions buccales peuvent \u00eatre associ\u00e9s.<\/li>\r\n                <li><strong>Que faire ?:<\/strong> Ce tableau est annonciateur d'une maladie syst\u00e9mique. Les traitements capillaires locaux sont inefficaces ; des tests s\u00e9rologiques doivent \u00eatre effectu\u00e9s pr\u00e9cocement et un traitement \u00e0 la p\u00e9nicilline doit \u00eatre initi\u00e9 sous surveillance sp\u00e9cialis\u00e9e. <\/li>\r\n            <\/ul>\r\n        <\/section>\r\n\r\n        <!-- Hekimler \u0130\u00e7in Klinik K\u0131lavuz -->\r\n        <section class=\"doctor-guide-box\">\r\n            <h3>\ud83e\ude7a Guide Clinique & M\u00e9dical pour les M\u00e9decins<\/h3>\r\n            <ul class=\"styled-list doctor-list\">\r\n                <li><strong>\u00c9tiologie et physiopathologie:<\/strong> Diss\u00e9mination syst\u00e9mique de la bact\u00e9rie <em>Treponema pallidum<\/em>, une esp\u00e8ce de spiroch\u00e8te. Endart\u00e9rite des vaisseaux entourant les follicules pileux et alop\u00e9cie isch\u00e9mique\/inflammatoire associ\u00e9e (alop\u00e9cie non cicatricielle). <\/li>\r\n                <li><strong>Crit\u00e8res diagnostiques et signes cliniques:<\/strong> Alop\u00e9cie de type \u00ab mit\u00e9e \u00bb observ\u00e9e chez environ 4 \u00e0 7 % des patients atteints de syphilis secondaire. Une perte des sourcils dans leur partie lat\u00e9rale peut \u00eatre associ\u00e9e. S\u00e9rologiquement, positivit\u00e9 des tests VDRL\/RPR et TPHA\/TPPA.  <\/li>\r\n                <li><strong>Signes dermoscopiques (trichoscopie):<\/strong> Absence de points noirs (extr\u00e9mit\u00e9s de cheveux cass\u00e9es), ostia folliculaires vides, \u00e9piderme interfolliculaire pr\u00e9serv\u00e9 et motifs vasculaires t\u00e9langiectasiques sur un fond jaun\u00e2tre-ros\u00e9.<\/li>\r\n                <li><strong>Diagnostic histopathologique (biopsie \u00e0 l'emporte-pi\u00e8ce) :<\/strong> \r\n                    <ul class=\"sub-list\">\r\n                        <li><em>Indication de biopsie:<\/em> Une biopsie \u00e0 l'emporte-pi\u00e8ce de 4 mm est pr\u00e9lev\u00e9e sur la l\u00e9sion en cas de suspicion dans les cas atypiques confondus avec l'alop\u00e9cie areata.<\/li>\r\n                        <li><em>Pathologie:<\/em> Infiltrat dense riche en plasmocytes dans les zones p\u00e9rivasculaire et p\u00e9rifolliculaire (l'infiltration plasmocytaire est tr\u00e8s typique de la syphilis) et signes d'endart\u00e9rite.<\/li>\r\n                    <\/ul>\r\n                <\/li>\r\n                <li><strong>Protocoles de Traitement Actuels :<\/strong> \r\n                    <ul class=\"sub-list\">\r\n                        <li><em>Traitement syst\u00e9mique:<\/em> Benzathine P\u00e9nicilline G 2,4 millions d'unit\u00e9s IM en dose unique (au stade secondaire). Doxycycline ou Azithromycine chez les patients allergiques \u00e0 la p\u00e9nicilline. Avec le traitement, les cheveux repoussent spontan\u00e9ment et compl\u00e8tement en quelques mois (sans cicatrice). De plus, pour les \u00e9valuations cliniques et chirurgicales, les <a href=\"https:\/\/www.muhammetozgehan.com.tr\" target=\"_blank\" rel=\"noopener\">approches sp\u00e9cialis\u00e9es et th\u00e9rapeutiques<\/a> peuvent \u00eatre examin\u00e9es.   <\/li>\r\n                    <\/ul>\r\n                <\/li>\r\n            <\/ul>\r\n        <\/section>\r\n\r\n        <!-- Bilimsel Referanslar -->\r\n        <section class=\"scientific-references-box\">\r\n            <h3>R\u00e9f\u00e9rences Scientifiques et Bibliographie<\/h3>\r\n            <ul class=\"ref-list\">\r\n                <li>Dai S, Wang H, Lin Z. Alop\u00e9cie mit\u00e9e dans la syphilis secondaire. <em>Int J Infect Dis<\/em>. 2019 mai;82:6. doi: 10.1016\/j.ijid.2019.02.023. Epub 2019 f\u00e9v 23. PMID: 30807867. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30807867\/\" target=\"_blank\" rel=\"noopener\">Lien PubMed<\/a><\/li>\r\n                <li>Saraswat N, Tripathy DM, Kumar S, Ranjan E, Madakshira MG, Goel S. Syphilis secondaire maligne se pr\u00e9sentant avec des l\u00e9sions rupio\u00efdes et une alop\u00e9cie mit\u00e9e. <em>Indian J Sex Transm Dis AIDS<\/em>. 2024 janv-juin;45(1):82-83. doi: 10.4103\/ijstd.ijstd_73_23. Epub 2024 juin 6. PMID: 38989088; PMCID: PMC11233054. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38989088\/\" target=\"_blank\" rel=\"noopener\">Lien PubMed<\/a><\/li>\r\n                <li>Jordaan HF, Louw M. L'alop\u00e9cie mit\u00e9e de la syphilis secondaire. Une \u00e9tude histopathologique de 12 patients. <em>Am J Dermatopathol<\/em>. 1995 avr;17(2):158-62. doi: 10.1097\/00000372-199504000-00008. PMID: 8600781. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8600781\/\" target=\"_blank\" rel=\"noopener\">Lien PubMed<\/a> <\/li>\r\n            <\/ul>\r\n        <\/section>\r\n    <\/article>\r\n<\/div>\r\n\r\n<style>\r\n.medical-guide-page-wrapper {\r\n    background-color: #0A192F;\r\n    padding: 60px 20px;\r\n    font-family: 'Segoe UI', Tahoma, Geneva, Verdana, sans-serif;\r\n    color: #FFFFFF;\r\n    max-width: 1000px;\r\n    margin: 0 auto;\r\n}\r\n\r\n.guide-hero {\r\n    text-align: center;\r\n    margin-bottom: 40px;\r\n}\r\n\r\n.hero-title-wrapper {\r\n    display: flex;\r\n    align-items: center;\r\n    justify-content: center;\r\n    gap: 12px;\r\n    margin-bottom: 10px;\r\n}\r\n\r\n.hero-logo-box {\r\n    background: linear-gradient(135deg, rgba(17, 34, 64, 0.9), rgba(10, 25, 47, 0.95));\r\n    border: 1px solid rgba(212, 175, 55, 0.4);\r\n    border-radius: 8px;\r\n    padding: 4px 8px;\r\n    display: flex !important;\r\n    align-items: center !important;\r\n    justify-content: center !important;\r\n    width: 44px !important;\r\n    height: 44px !important;\r\n    box-shadow: 0 4px 15px rgba(0,0,0,0.3);\r\n    flex-shrink: 0;\r\n}\r\n\r\n.hero-inline-logo {\r\n    width: 32px !important;\r\n    height: 32px !important;\r\n    max-width: 32px !important;\r\n    max-height: 32px !important;\r\n    object-fit: contain !important;\r\n}\r\n\r\n.guide-subtitle {\r\n    color: #CBD5E1;\r\n    font-size: 15px;\r\n    margin: 0;\r\n}\r\n\r\n.medical-article-card {\r\n    background: linear-gradient(135deg, rgba(17, 34, 64, 0.85), rgba(10, 25, 47, 0.95));\r\n    border: 1px solid rgba(212, 175, 55, 0.3);\r\n    border-radius: 16px;\r\n    padding: 40px;\r\n    box-shadow: 0 10px 30px rgba(0,0,0,0.4);\r\n}\r\n\r\n.article-header {\r\n    border-bottom: 1px solid rgba(212, 175, 55, 0.2);\r\n    padding-bottom: 25px;\r\n    margin-bottom: 30px;\r\n}\r\n\r\n.article-category {\r\n    display: inline-block;\r\n    color: #D4AF37;\r\n    font-size: 10px;\r\n    font-weight: 700;\r\n    text-transform: uppercase;\r\n    letter-spacing: 2px;\r\n    background: rgba(212, 175, 55, 0.1);\r\n    padding: 4px 10px;\r\n    border-radius: 4px;\r\n    margin-bottom: 15px;\r\n}\r\n\r\n.medical-article-card h1 {\r\n    font-size: 28px;\r\n    color: #FFFFFF;\r\n    margin: 0 0 15px 0;\r\n    font-weight: 700;\r\n    line-height: 1.3;\r\n}\r\n\r\n.author-meta-box p {\r\n    font-size: 14px;\r\n    color: #CBD5E1;\r\n    margin: 3px 0;\r\n}\r\n\r\n.compilation-note {\r\n    color: #94A3B8;\r\n    font-size: 13px;\r\n}\r\n\r\n.medical-illustration-box {\r\n    margin: 30px 0;\r\n    text-align: center;\r\n    background: rgba(0, 0, 0, 0.2);\r\n    padding: 15px;\r\n    border-radius: 10px;\r\n    border: 1px solid rgba(255, 255, 255, 0.05);\r\n}\r\n\r\n.medical-illustration-box img {\r\n    max-width: 100%;\r\n    height: auto;\r\n    border-radius: 8px;\r\n    box-shadow: 0 4px 15px rgba(0,0,0,0.3);\r\n}\r\n\r\n.patient-info-box, .doctor-guide-box, .scientific-references-box {\r\n    margin-top: 35px;\r\n    background: rgba(10, 25, 47, 0.6);\r\n    border: 1px solid rgba(212, 175, 55, 0.2);\r\n    border-radius: 12px;\r\n    padding: 25px;\r\n}\r\n\r\n.medical-article-card h3 {\r\n    font-size: 18px;\r\n    color: #D4AF37;\r\n    margin-top: 0;\r\n    margin-bottom: 15px;\r\n    font-weight: 600;\r\n}\r\n\r\n.medical-article-card p, .medical-article-card li {\r\n    font-size: 14px;\r\n    color: #CBD5E1;\r\n    line-height: 1.6;\r\n}\r\n\r\n.styled-list {\r\n    padding-left: 20px;\r\n    margin: 10px 0;\r\n}\r\n\r\n.styled-list li {\r\n    margin-bottom: 10px;\r\n}\r\n\r\n.sub-list {\r\n    margin-top: 8px;\r\n    padding-left: 20px;\r\n    list-style-type: circle;\r\n}\r\n\r\n.scientific-references-box {\r\n    border-top: 1px solid rgba(212, 175, 55, 0.3);\r\n}\r\n\r\n.ref-list {\r\n    padding-left: 20px;\r\n    font-size: 13px;\r\n    color: #94A3B8;\r\n}\r\n\r\n.ref-list li {\r\n    margin-bottom: 12px;\r\n}\r\n\r\n.medical-article-card a {\r\n    color: #D4AF37;\r\n    text-decoration: underline;\r\n    transition: color 0.3s ease;\r\n}\r\n\r\n.medical-article-card a:hover {\r\n    color: #f3d06c;\r\n}\r\n\r\n\/* Mobil Uyumluluk *\/\r\n@media (max-width: 768px) {\r\n    .medical-article-card {\r\n        padding: 20px;\r\n    }\r\n    .medical-article-card h1 {\r\n        font-size: 22px;\r\n    }\r\n}\r\n<\/style>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Encyclop\u00e9die M\u00e9dicale Capillaire Pathologies dermatologiques et guides cliniques fond\u00e9s sur des preuves, selon les normes internationales. GUIDE CLINIQUE &#038; PATHOLOGIE Atteinte capillaire des infections syst\u00e9miques (Syphilis secondaire et alop\u00e9cie \u00ab mit\u00e9e \u00bb) \u2013 Guide de diagnostic et de traitement Pr\u00e9par\u00e9 par : Dr. Muhammet \u00d6zgehan | Association Turque des Maladies des Cheveux et du Cuir [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1175","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/pages\/1175","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/comments?post=1175"}],"version-history":[{"count":0,"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/pages\/1175\/revisions"}],"wp:attachment":[{"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/media?parent=1175"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}