{"id":955,"date":"2026-10-04T18:49:08","date_gmt":"2026-10-04T18:49:08","guid":{"rendered":"https:\/\/muhammetozgehan.com\/?page_id=955"},"modified":"2026-10-10T00:31:20","modified_gmt":"2026-10-10T00:31:20","slug":"atteinte-du-cuir-chevelu-dans-la-lepre-et-les-maladies-granulomateuses","status":"publish","type":"page","link":"https:\/\/muhammetozgehan.com\/fr\/atteinte-du-cuir-chevelu-dans-la-lepre-et-les-maladies-granulomateuses\/","title":{"rendered":"Atteinte du cuir chevelu dans la l\u00e8pre et les maladies granulomateuses"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"955\" class=\"elementor elementor-955 elementor-334\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-01d7e7d e-flex e-con-boxed e-con e-parent\" data-id=\"01d7e7d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a0185cd elementor-widget elementor-widget-html\" data-id=\"a0185cd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div class=\"medical-guide-page-wrapper\">\r\n    <!-- Sayfa \u00dcst\u00fc K\u00fcresel Ba\u015fl\u0131k & Logo Alan\u0131 -->\r\n    <div class=\"guide-hero\">\r\n        <div class=\"hero-title-wrapper\">\r\n            <div class=\"hero-logo-box\">\r\n                <img decoding=\"async\" src=\"https:\/\/muhammetozgehan.com\/wp-content\/uploads\/2026\/10\/logo-seffaf.png\" alt=\"Logo du Dr Muhammet \u00d6zgehan\" width=\"32\" height=\"32\" class=\"hero-inline-logo\" title=\"\">\r\n            <\/div>\r\n            <h2>Encyclop\u00e9die M\u00e9dicale Capillaire<\/h2>\r\n        <\/div>\r\n        <p class=\"guide-subtitle\">Pathologies dermatologiques et guides cliniques fond\u00e9s sur des preuves, selon les normes internationales.<\/p>\r\n    <\/div>\r\n\r\n    <!-- Ana Makale Konteyneri -->\r\n    <article class=\"medical-article-card\">\r\n        <div class=\"article-header\">\r\n            <span class=\"article-category\">GUIDE CLINIQUE & PATHOLOGIE<\/span>\r\n            <h1>Atteinte du cuir chevelu dans la l\u00e8pre et les maladies granulomateuses \u2013 Guide de diagnostic et de traitement<\/h1>\r\n            <div class=\"author-meta-box\">\r\n                <p><strong>Pr\u00e9par\u00e9 par :<\/strong> Dr. Muhammet \u00d6zgehan | Association Turque des Maladies des Cheveux et du Cuir Chevelu<\/p>\r\n                <p class=\"compilation-note\"><em>Ce guide a \u00e9t\u00e9 compil\u00e9 par le Dr Muhammet \u00d6zgehan, en se basant sur la litt\u00e9rature actuelle.<\/em><\/p>\r\n            <\/div>\r\n        <\/div>\r\n\r\n        <!-- Medikal \u0130ll\u00fcstrasyon Alan\u0131 -->\r\n        <div class=\"medical-illustration-box\">\r\n            <img decoding=\"async\" src=\"https:\/\/sachastaliklari.org.tr\/wp-content\/uploads\/2026\/09\/leprosy-hansen-disease-granulomatous-diseases-scalp-dr-muhammet-ozgehan.png\" alt=\"Illustration de l\u2019atteinte granulomateuse du cuir chevelu dans la l\u00e8pre (maladie de Hansen)\" title=\"\">\r\n        <\/div>\r\n\r\n        <!-- Hasta Bilgilendirme B\u00f6l\u00fcm\u00fc -->\r\n        <section class=\"patient-info-box\">\r\n            <h3>\ud83d\udccc Section d'Information pour les Patients : Que Signifie Cette Condition ?<\/h3>\r\n            <p>La l\u00e8pre (maladie de Hansen) est une maladie infectieuse granulomateuse chronique caus\u00e9e par la bact\u00e9rie <em>Mycobacterium leprae<\/em>, qui affecte les nerfs p\u00e9riph\u00e9riques et la peau. Bien que rare, elle peut entra\u00eener des pertes de poils et de cheveux caract\u00e9ristiques sur le cuir chevelu et le visage. <\/p>\r\n            <ul class=\"styled-list\">\r\n                <li><strong>Atteinte des cheveux et des sourcils :<\/strong> Dans la l\u00e8pre, en particulier dans sa forme l\u00e9promateuse, une chute des sourcils commen\u00e7ant par la partie externe (madarose) et des pertes de cheveux permanentes accompagn\u00e9es de nodules et de plaques granulomateuses sur le cuir chevelu peuvent se d\u00e9velopper.<\/li>\r\n                <li><strong>Autres signes :<\/strong> Perte de sensibilit\u00e9 cutan\u00e9e (taches p\u00e2les avec perte de sensation de chaud-froid et de douleur), \u00e9paississement du lobe de l\u2019oreille, atteintes nerveuses et signes asym\u00e9triques sur le visage.<\/li>\r\n                <li><strong>Que faire ? :<\/strong> C\u2019est une maladie enti\u00e8rement curable gr\u00e2ce \u00e0 des combinaisons de m\u00e9dicaments (polychimioth\u00e9rapie \u2013 PCT). Un diagnostic pr\u00e9coce est vital pour pr\u00e9venir des l\u00e9sions nerveuses permanentes. <\/li>\r\n            <\/ul>\r\n        <\/section>\r\n\r\n        <!-- Hekimler \u0130\u00e7in Klinik K\u0131lavuz -->\r\n        <section class=\"doctor-guide-box\">\r\n            <h3>\ud83e\ude7a Guide Clinique & M\u00e9dical pour les M\u00e9decins<\/h3>\r\n            <ul class=\"styled-list doctor-list\">\r\n                <li><strong>\u00c9tiologie et physiopathologie :<\/strong> <em>Mycobacterium leprae<\/em> ou <em>Mycobacterium lepromatosis<\/em> sont les agents \u00e9tiologiques. Les bacilles pr\u00e9f\u00e8rent les zones corporelles plus froides (lobe de l\u2019oreille, muqueuse nasale, p\u00e9riph\u00e9rie du cuir chevelu). Ils infiltrent les follicules pileux et les terminaisons nerveuses avec une inflammation granulomateuse, provoquant des alop\u00e9cies cicatricielles ou non cicatricielles.  <\/li>\r\n                <li><strong>Crit\u00e8res diagnostiques et signes cliniques :<\/strong> Chute du tiers lat\u00e9ral des sourcils (madarose), l\u00e9sions infiltrantes sur le cuir chevelu, nodules et l\u00e9sions avec d\u00e9ficit sensoriel. \u00c9paississement des grands nerfs auriculaires. <\/li>\r\n                <li><strong>Diagnostic Histopathologique (Biopsie au Punch) :<\/strong> \r\n                    <ul class=\"sub-list\">\r\n                        <li><em>Indication de la biopsie :<\/em> Une biopsie \u00e0 l\u2019emporte-pi\u00e8ce de 4 mm est pr\u00e9lev\u00e9e sur les l\u00e9sions suspectes du cuir chevelu ou du visage.<\/li>\r\n                        <li><em>Pathologie :<\/em> Granulomes compos\u00e9s de cellules \u00e9pith\u00e9lio\u00efdes, de cellules de Virchow (macrophages spumeux) et de lymphocytes dans le derme. Mise en \u00e9vidence d\u2019amas de bacilles intracellulaires (globi) par coloration de Fite-Faraco ou de Ziehl-Neelsen. <\/li>\r\n                    <\/ul>\r\n                <\/li>\r\n                <li><strong>Protocoles de Traitement Actuels :<\/strong> \r\n                    <ul class=\"sub-list\">\r\n                        <li><em>Polychimioth\u00e9rapie (PCT) :<\/em> Des combinaisons de Rifampicine, Dapsone et Clofazimine sont administr\u00e9es sans interruption (pendant 6 mois \u00e0 2 ans selon le type de maladie), conform\u00e9ment au protocole de l\u2019Organisation Mondiale de la Sant\u00e9 (OMS). De plus, des <a href=\"https:\/\/www.muhammetozgehan.com.tr\" target=\"_blank\" rel=\"noopener\">approches sp\u00e9cialis\u00e9es et th\u00e9rapeutiques<\/a> peuvent \u00eatre examin\u00e9es pour les \u00e9valuations cliniques et chirurgicales. <\/li>\r\n                    <\/ul>\r\n                <\/li>\r\n            <\/ul>\r\n        <\/section>\r\n\r\n        <!-- Bilimsel Referanslar -->\r\n        <section class=\"scientific-references-box\">\r\n            <h3>R\u00e9f\u00e9rences Scientifiques et Bibliographie<\/h3>\r\n            <ul class=\"ref-list\">\r\n                <li>Kaya D, Garnes ND, Robins A, Su SY, Ginsberg LE, Chen MM. Leprosy of the great auricular nerve: case report and review of the literature. <em>Clin Imaging<\/em>. 2022 Feb;82:63-66. doi: 10.1016\/j.clinimag.2021.10.001. Epub 2021 Oct 15. PMID: 34775253. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34775253\/\" target=\"_blank\" rel=\"noopener\">Lien PubMed<\/a> <\/li>\r\n                <li>Concha R M, Cossio T ML, Salazar S I, Fich S F, P\u00e9rez C C, Gonz\u00e1lez B S. Enfermedad de Hansen: Revisi\u00f3n a prop\u00f3sito de un caso [Maladie de Hansen : rapport de cas et revue de la litt\u00e9rature]. <em>Rev Chilena Infectol<\/em>. 2008 Feb;25(1):64-9. Espagnol. PMID: 18273528. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18273528\/\" target=\"_blank\" rel=\"noopener\">Lien PubMed<\/a><\/li>\r\n                <li>Thaipisuttikul Y, Kateruttanakul P. Sarcoidosis mimics lepromatous leprosy: a case report. <em>J Med Assoc Thai<\/em>. 2007 Jan;90(1):171-4. PMID: 17621750. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17621750\/\" target=\"_blank\" rel=\"noopener\">Lien PubMed<\/a><\/li>\r\n            <\/ul>\r\n        <\/section>\r\n    <\/article>\r\n<\/div>\r\n\r\n<style>\r\n.medical-guide-page-wrapper {\r\n    background-color: #0A192F;\r\n    padding: 60px 20px;\r\n    font-family: 'Segoe UI', Tahoma, Geneva, Verdana, sans-serif;\r\n    color: #FFFFFF;\r\n    max-width: 1000px;\r\n    margin: 0 auto;\r\n}\r\n\r\n.guide-hero {\r\n    text-align: center;\r\n    margin-bottom: 40px;\r\n}\r\n\r\n.hero-title-wrapper {\r\n    display: flex;\r\n    align-items: center;\r\n    justify-content: center;\r\n    gap: 12px;\r\n    margin-bottom: 10px;\r\n}\r\n\r\n.hero-logo-box {\r\n    background: linear-gradient(135deg, rgba(17, 34, 64, 0.9), rgba(10, 25, 47, 0.95));\r\n    border: 1px solid rgba(212, 175, 55, 0.4);\r\n    border-radius: 8px;\r\n    padding: 4px 8px;\r\n    display: flex !important;\r\n    align-items: center !important;\r\n    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  <h2>L\u00e8pre (Maladie de Hansen) et atteinte du cuir chevelu dans les maladies granulomateuses \u2013 Questions fr\u00e9quentes<\/h2>\r\n        <p>Ce que vous devez savoir sur l\u2019impact de la l\u00e8pre (maladie de Hansen) et des maladies granulomateuses sur le cuir chevelu, les processus d\u2019alop\u00e9cie cicatricielle et les approches th\u00e9rapeutiques, avec l\u2019expertise de la clinique du Dr Muhammet \u00d6zgehan.<\/p>\r\n    <\/div>\r\n\r\n    <div class=\"faq-accordion\">\r\n        <!-- Soru 1 -->\r\n        <div class=\"faq-item\">\r\n            <button class=\"faq-question\" type=\"button\" onclick=\"toggleFaqLepra(this)\">\r\n                <span>1. Comment la l\u00e8pre (maladie de Hansen) affecte-t-elle le cuir chevelu et les follicules pileux ?<\/span>\r\n                <span class=\"faq-icon\">+<\/span>\r\n            <\/button>\r\n            <div class=\"faq-answer\">\r\n                <div class=\"faq-inner-text\">\r\n                    <p>La l\u00e8pre (une maladie infectieuse chronique caus\u00e9e par la bact\u00e9rie *Mycobacterium leprae*) est une maladie granulomateuse qui cible les nerfs et la peau. Lorsqu\u2019elle affecte le cuir chevelu, en particulier dans les formes de l\u00e8pre l\u00e9promateuse, des infiltrations, des nodules et des pertes de sensibilit\u00e9 dues \u00e0 des l\u00e9sions nerveuses peuvent \u00eatre observ\u00e9s. Le <strong>Dr Muhammet \u00d6zgehan<\/strong> indique que ce processus granulomateux peut perturber les unit\u00e9s folliculaires, entra\u00eenant des pertes de cheveux localis\u00e9es. <\/p>\r\n                <\/div>\r\n            <\/div>\r\n        <\/div>\r\n\r\n        <!-- Soru 2 -->\r\n        <div class=\"faq-item\">\r\n            <button class=\"faq-question\" type=\"button\" onclick=\"toggleFaqLepra(this)\">\r\n                <span>2. Les maladies granulomateuses provoquent-elles une chute de cheveux permanente (alop\u00e9cie cicatricielle) ?<\/span>\r\n                <span class=\"faq-icon\">+<\/span>\r\n            <\/button>\r\n            <div class=\"faq-answer\">\r\n                <div class=\"faq-inner-text\">\r\n                    <p>Oui, la l\u00e8pre et les maladies granulomateuses profondes similaires peuvent entra\u00eener des tableaux d\u2019<strong>alop\u00e9cie cicatricielle (permanente)<\/strong>, car elles d\u00e9clenchent une inflammation chronique et le d\u00e9veloppement de tissu conjonctif (cicatrice) dans les tissus. Les racines des cheveux sont irr\u00e9versiblement d\u00e9truites dans les zones o\u00f9 les granulomes se sont install\u00e9s. Le <strong>Dr Muhammet \u00d6zgehan<\/strong> souligne que le diagnostic pr\u00e9coce dans de telles infections syst\u00e9miques et granulomateuses est vital pour pr\u00e9venir les l\u00e9sions tissulaires et la calvitie permanente. <\/p>\r\n                <\/div>\r\n            <\/div>\r\n        <\/div>\r\n\r\n        <!-- Soru 3 -->\r\n        <div class=\"faq-item\">\r\n            <button class=\"faq-question\" type=\"button\" onclick=\"toggleFaqLepra(this)\">\r\n                <span>3. Quelles approches cliniques sont appliqu\u00e9es dans la l\u00e8pre et l\u2019atteinte granulomateuse du cuir chevelu ?<\/span>\r\n                <span class=\"faq-icon\">+<\/span>\r\n            <\/button>\r\n            <div class=\"faq-answer\">\r\n                <div class=\"faq-inner-text\">\r\n                    <p>L\u2019objectif principal du traitement est d\u2019arr\u00eater compl\u00e8tement l\u2019agent microbien ou l\u2019inflammation syst\u00e9mique sous-jacente. Les approches actuelles suivies \u00e0 la clinique du <strong>Dr Muhammet \u00d6zgehan<\/strong> et lors des consultations dermatologiques sont les suivantes :<\/p>\r\n                    <ul>\r\n                        <li><strong>Traitements syst\u00e9miques multidisciplinaires :<\/strong> Protocoles d\u2019antibiotiques multiples \u00e0 long terme (antileptiques combin\u00e9s) sous contr\u00f4le m\u00e9dical pour les infections sp\u00e9cifiques comme la l\u00e8pre.<\/li>\r\n                        <li><strong>Biopsie cutan\u00e9e et analyse pathologique :<\/strong> Examen histopathologique de la pr\u00e9sence de granulomes et de bact\u00e9ries pour un diagnostic d\u00e9finitif des l\u00e9sions du cuir chevelu.<\/li>\r\n                        <li><strong>Gestion de l\u2019inflammation et des cicatrices :<\/strong> Soins m\u00e9dicaux de soutien approuv\u00e9s par le m\u00e9decin pour minimiser les l\u00e9sions tissulaires et g\u00e9rer les s\u00e9quelles.<\/li>\r\n                    <\/ul>\r\n                <\/div>\r\n            <\/div>\r\n        <\/div>\r\n\r\n        <!-- Soru 4 -->\r\n        <div class=\"faq-item\">\r\n            <button class=\"faq-question\" type=\"button\" onclick=\"toggleFaqLepra(this)\">\r\n                <span>4. Une greffe de cheveux est-elle possible pour les personnes ayant eu la l\u00e8pre ou une maladie granulomateuse ?<\/span>\r\n                <span class=\"faq-icon\">+<\/span>\r\n            <\/button>\r\n            <div class=\"faq-answer\">\r\n                <div class=\"faq-inner-text\">\r\n                    <p>La greffe de cheveux est absolument contre-indiqu\u00e9e (non r\u00e9alis\u00e9e) pendant les p\u00e9riodes o\u00f9 la maladie est active, le traitement n\u2019est pas termin\u00e9 ou l\u2019inflammation tissulaire persiste. Le <strong>Dr Muhammet \u00d6zgehan<\/strong> indique que les interventions chirurgicales effectu\u00e9es avant la gu\u00e9rison compl\u00e8te de l\u2019infection et la stabilisation du tissu cicatriciel peuvent \u00e0 la fois d\u00e9clencher l\u2019infection et rendre l\u2019int\u00e9gration des greffons impossible. Cependant, si la maladie est compl\u00e8tement gu\u00e9rie depuis des ann\u00e9es, une \u00e9valuation peut \u00eatre effectu\u00e9e dans des cas tr\u00e8s s\u00e9lectionn\u00e9s apr\u00e8s analyse de la qualit\u00e9 des tissus. <\/p>\r\n                <\/div>\r\n            <\/div>\r\n        <\/div>\r\n\r\n        <!-- Soru 5 -->\r\n        <div class=\"faq-item\">\r\n            <button class=\"faq-question\" type=\"button\" onclick=\"toggleFaqLepra(this)\">\r\n                <span>5. \u00c0 quoi faut-il faire attention pour la sant\u00e9 des cheveux dans de telles maladies dermatologiques graves ?<\/span>\r\n                <span class=\"faq-icon\">+<\/span>\r\n            <\/button>\r\n            <div class=\"faq-answer\">\r\n                <div class=\"faq-inner-text\">\r\n                    <p>Le suivi des affections cutan\u00e9es syst\u00e9miques et granulomateuses exige une grande rigueur. Le <strong>Dr Muhammet \u00d6zgehan<\/strong> fait les recommandations suivantes aux personnes ayant travers\u00e9 ce processus :<\/p>\r\n                    <ul>\r\n                        <li>Ne jamais n\u00e9gliger les cures de traitement syst\u00e9mique et les contr\u00f4les prescrits par le m\u00e9decin.<\/li>\r\n                        <li>Signaler imm\u00e9diatement au dermatologue la moindre perte de sensibilit\u00e9, changement de couleur, nodule ou cicatrice sur le cuir chevelu.<\/li>\r\n                        <li>Prot\u00e9ger soigneusement la peau des traumatismes et des irritants chimiques.<\/li>\r\n                    <\/ul>\r\n                <\/div>\r\n            <\/div>\r\n        <\/div>\r\n    <\/div>\r\n<\/div>\r\n\r\n<!-- Standart Klinik CTA \/ Ba\u015fvuru Butonu Alan\u0131 -->\r\n<div class=\"mo-clinic-cta-wrapper\">\r\n    <div class=\"mo-cta-box\">\r\n        <h3>Pour vos questions et un rendez-vous de consultation clinique<\/h3>\r\n        <p>Pour toute question concernant la l\u00e8pre, les maladies granulomateuses du cuir chevelu et la planification du traitement, ou pour prendre un rendez-vous de consultation, vous pouvez contacter la <strong>Clinique du Dr Muhammet \u00d6zgehan<\/strong> d\u00e8s maintenant.<\/p>\r\n        \r\n        <div class=\"mo-cta-buttons\">\r\n            <a href=\"https:\/\/wa.me\/905327220233?text=Merhaba,%20lepra%20ve%20gran%C3%BClomat%C3%B6z%20hastal%C4%B1klarda%20sa%C3%A7%20derisi%20tutulumu%20ile%20ilgili%20bilgi%20ve%20muayene%20randevusu%20almak%20istiyorum.\" target=\"_blank\" rel=\"noopener\" class=\"mo-btn mo-wa\">\r\n                <span class=\"mo-icon\">\ud83d\udcac<\/span>\r\n                <div class=\"mo-text\">\r\n                    <small>Via WhatsApp<\/small>\r\n                    <span>Obtenez des informations & un rendez-vous imm\u00e9diat<\/span>\r\n                <\/div>\r\n            <\/a>\r\n\r\n            <a href=\"tel:+905327220233\" class=\"mo-btn mo-call\">\r\n                <span class=\"mo-icon\">\ud83d\udcde<\/span>\r\n                <div class=\"mo-text\">\r\n                    <small>Appel Direct<\/small>\r\n                    <span>+90 532 722 02 33<\/span>\r\n                <\/div>\r\n            <\/a>\r\n        <\/div>\r\n    <\/div>\r\n<\/div>\r\n\r\n<style>\r\n    .alopecia-faq-container {\r\n        max-width: 1140px;\r\n        width: 100%;\r\n        margin: 40px auto 20px auto;\r\n        background-color: #111111;\r\n        border: 1px solid #333333;\r\n        border-top: 4px solid #D4AF37;\r\n        padding: 40px;\r\n        border-radius: 10px;\r\n        font-family: -apple-system, BlinkMacSystemFont, \"Segoe UI\", Roboto, sans-serif;\r\n        color: #e0e0e0;\r\n        box-shadow: 0 6px 20px rgba(0,0,0,0.8);\r\n        box-sizing: border-box;\r\n    }\r\n    .faq-header {\r\n        text-align: center;\r\n        margin-bottom: 35px;\r\n    }\r\n    .faq-header h2 {\r\n        color: #D4AF37;\r\n        font-size: 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GUIDE CLINIQUE &#038; PATHOLOGIE Atteinte du cuir chevelu dans la l\u00e8pre et les maladies granulomateuses \u2013 Guide de diagnostic et de traitement Pr\u00e9par\u00e9 par : Dr. Muhammet \u00d6zgehan | Association Turque des Maladies des Cheveux et du Cuir Chevelu [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-955","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/pages\/955","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/comments?post=955"}],"version-history":[{"count":0,"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/pages\/955\/revisions"}],"wp:attachment":[{"href":"https:\/\/muhammetozgehan.com\/fr\/wp-json\/wp\/v2\/media?parent=955"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}